Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Obinutuzumab shows promise in preserving kidney function, preventing flares in lupus nephritis patients

In a post hoc analysis of the phase 2 NOBILITY trial, researchers found that treatment with obinutuzumab-;an antibody that targets a protein expressed on certain immune cells-;was superior to placebo for preserving kidney function and preventing flares in patients with lupus nephritis, a kidney condition associated with the autoimmune disease lupus.

10 Nov 2023

High levels of anti-Ro/SSA antibodies linked to fetal heart block in pregnant women

Some individuals with anti-Ro/SSA antibodies (anti–Sjögren's-syndrome–related antigen A autoantibodies, also called anti-Ro antibodies) have autoimmune diseases such as lupus or Sjögren's syndrome, but many have no symptoms.

10 Nov 2023

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

A new paper recently published in Nature, reported the examination of synovial tissue from the joints of nearly 80 people with RA, in combination with RNA sequencing and surface protein analyses.

10 Nov 2023

Pediatric viral threats surge in the 21st century: A call for One Health approach

Scoping review in "Pediatric Research" examines the rise of pediatric viral diseases in the 21st century and underscores the importance of a One Health approach, integrating human, animal, and ecosystem health, to combat these emerging and re-emerging infectious threats effectively.

9 Nov 2023

Study links lower testosterone levels with increased arthritis risk

The relationship between serological testosterone levels and arthritis among United States (US) adults.

9 Nov 2023

Study unravels molecular basis of chronic pain transition

Researchers from the Center for Translational Immunology at University Medical Center Utrecht (the Netherlands) have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution.

8 Nov 2023

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation that leads to pain, joint damage, and disability, which affects approximately 18 million people worldwide.

8 Nov 2023

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

New research at ACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus while maintaining a robust response to vaccines.

7 Nov 2023

New training program expands access to rheumatology care for Native American communities

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, describes the expansion of a novel program to train primary care physicians (PCPs) in the diagnosis and management of rheumatoid arthritis (RA) in Native American communities that have little or no access to rheumatology care.

7 Nov 2023

Experts develop equitable quality measures to improve lupus care by 2030

Leaders of a project to develop and implement equitable new quality measures for lupus care by the end of the decade will present their work at ACR Convergence 2023, the American College of Rheumatology's annual meeting.

7 Nov 2023

Deep learning system accurately identifies joint space narrowing and erosions in hand radiographs

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that a deep learning system could accurately identify and predict joint space narrowing and erosions in hand radiographs of patients with rheumatoid arthritis (RA).

7 Nov 2023

Positive antiphospholipid antibodies linked to increased cardiovascular risk in lupus patients

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, describes a link between positive antiphospholipid antibodies and an increased risk of future cardiovascular disease in patients with systemic lupus erythematosus (SLE).

7 Nov 2023

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that ultrasound-detected salivary gland abnormalities in primary Sjögren's become more severe over time and that the slow-to-progress disease likely starts long before it is first detected.

7 Nov 2023

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, found that JAK inhibitors (JAKi) and tocilizumab elicited better response rates in VEXAS syndrome compared to other targeted therapies.

7 Nov 2023

$Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis$

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

Researchers will present the first-ever study of fractures and calcium pyrophosphate deposition disease at ACR Convergence 2023, the American College of Rheumatology's annual meeting.

7 Nov 2023

Daily fetal heart rate monitoring recommended for pregnant women with high anti-SSA/Ro antibodies

Physicians who care for pregnant women have long sought to identify which of their patients would most likely benefit from monitoring of their fetus's heart rate to catch early signs of their unborn child developing heart problems tied to the mother's immune system.

7 Nov 2023

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

According to new research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, continuing tumor necrosis factor inhibitors during pregnancy is not associated with worse fetal or obstetric outcomes and may reduce the risk of severe maternal infections during pregnancy (Abstract #0477).

7 Nov 2023

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Obinutuzumab shows promise in preserving kidney function, preventing flares in lupus nephritis patients

High levels of anti-Ro/SSA antibodies linked to fetal heart block in pregnant women

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

Pediatric viral threats surge in the 21st century: A call for One Health approach

Study links lower testosterone levels with increased arthritis risk

Study unravels molecular basis of chronic pain transition

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

New training program expands access to rheumatology care for Native American communities

Experts develop equitable quality measures to improve lupus care by 2030

Deep learning system accurately identifies joint space narrowing and erosions in hand radiographs

Positive antiphospholipid antibodies linked to increased cardiovascular risk in lupus patients

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

Daily fetal heart rate monitoring recommended for pregnant women with high anti-SSA/Ro antibodies

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

Study shows depression increases disability risk in rheumatoid arthritis sufferers

Shifting towards personalized treatment approaches for chronic inflammatory diseases

New exercise trial aims to improve quality of life for people with rheumatoid arthritis

How medical manufacturing trends are evolving: From performance testing to 3D vision

Utilizing firefly liquid handling for laboratory developed tests

Immunopeptidomics offer new hope in cancer research

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

How medical manufacturing trends are evolving: From performance testing to 3D vision

Utilizing firefly liquid handling for laboratory developed tests

Immunopeptidomics offer new hope in cancer research

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