Mpox News and Research

Latest Mpox News and Research

Discovery of a potential new target for new MPOX or broad pox vaccines

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and identification of antigens of MPXV IIa clade and IIb clade, in comparison to recipients of smallpox vaccines (ACAM2000 and IMVANEX).

12 Jan 2023

Clinical and genomic signatures of monkeypox outbreaks in 2022

Announcing a new article publication for Zoonoses journal. The monkeypox outbreaks started in 2022 and became an unexpected public health emergency of international concern (PHEIC).

11 Jan 2023

The main source of editing of the mpox virus genome during the 2022 outbreak

Researchers investigated the main source of editing of the 2022 mpox virus genome.

11 Jan 2023

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

Researchers from Nigeria and the United Kingdom (U.K.) analyzed mpox virus genomes and found that divergent lineages of the mpox virus exhibiting human-to-human transmission existed in the Nigerian population before the 2022 spread of the virus outside of the endemic regions.

10 Jan 2023

Old antibiotic nitroxoline suggested as a treatment for MPOX

In a recent study posted to the bioRxiv* server, researchers in Germany investigated the effectiveness of the antibiotic nitroxoline against the currently circulating mpox viruses, previously called monkeypox virus (MPXV). This antibiotic has been used in Europe for about fifty years and has been proven effective in fighting biofilm infections.

3 Jan 2023

Study suggests a single dose of JYNNEOS vaccine may lessen the severity of mpox illness

Researchers pursued evidence that the JYNNEOS vaccine offered some protection against the mpox disease, especially they confirmed the duration for which the one dose of this vaccine conferred protection.

3 Jan 2023

Diagnostic technologies in Asia Pacific are key to progress toward health-related SDGs

We are at the halfway point from when we set our ambitious sustainable development goal 3 (SDG3) for good health and well-being by 2030.

23 Dec 2022

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Researchers described a messenger ribonucleic acid (mRNA)-lipid nanoparticle monkeypox vaccine encoding four conserved monkeypox virus surface proteins which induced monkeypox virus-specific immunity and elicited heterologous protection when challenged with lethal vaccinia virus.

23 Dec 2022

Single-dose smallpox vaccine could be effective against mpox

Researchers estimated the efficacy of a single-dose Modified Vaccinia Ankara-Bavaria Nordic (MVA-BN) vaccine against mpox (MPX) in gay, bisexual, and other men who have sex with men (GBMSM).

19 Dec 2022

Study examines Mpox prevention with modified vaccinia Ankara (MVA)

A new Eurosurveillance study investigated the efficacy of the MVA-BN vaccine, which was administered to individuals after exposure to the virus.

18 Dec 2022

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus.

16 Dec 2022

The mpox viral load kinetics over time in various parts of the body

Researchers characterized the time to mpox virus clearance of immunocompetent individuals with mild MPX in a real-world community-based setting utilizing longitudinal information.

16 Dec 2022

How do predicted ecological niches of the mpox virus compare with that of 99 mammal species?

Researchers compared ecological niches to identify probable mpox virus reservoir hosts.

15 Dec 2022

New approach to detect misinformation in an emergent health domain on social media

A paper coauthored by PhD student Lanyu Shang and members of Associate Professor Dong Wang's research group, the Social Sensing and Intelligence Lab in the School of Information Sciences at the University of Illinois Urbana-Champaign, received the best paper award in the research track during the 2022 IEEE/ACM International Conference on Advances in Social Network Analysis and Mining (ASONAM 2022).

13 Dec 2022

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Researchers provided an overview of existing molecular methods for mpox virus detection.

13 Dec 2022

Knowledge and attitudes to mpox among GBMSM in Australia

Researchers presented the results of a cross-sectional survey done in Australia between August and September 2022.

12 Dec 2022

Reports of Mpox disease following recent vaccination

The risk of infection and development of severe symptoms for Mpox remains, even after vaccination

11 Dec 2022

Enveloped viruses show greater cross-species transmission, according to new research

New research found that enveloped viruses harbor greater cross-species transmissibility and are more likely to cause zoonotic infections than nonenveloped viruses.

9 Dec 2022

Improved early detection and analysis of airborne pathogens with new liquid-coated air filters

Researchers from the University of Maine and University of Massachusetts Amherst have designed new liquid-coated air filters that allow for improved early detection and analysis of airborne bacteria and viruses, including the one that causes COVID-19.

7 Dec 2022

Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

Researchers evaluated the immunogenicity, boosting efficacy, and safety of single-dose and two-dose MVA-BN (modified vaccinia Ankara-Bavarian Nordic) vaccinations in comparison to replicating smallpox vaccines.

7 Dec 2022

Mpox News and Research

Latest Mpox News and Research

Discovery of a potential new target for new MPOX or broad pox vaccines

Clinical and genomic signatures of monkeypox outbreaks in 2022

The main source of editing of the mpox virus genome during the 2022 outbreak

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

Old antibiotic nitroxoline suggested as a treatment for MPOX

Study suggests a single dose of JYNNEOS vaccine may lessen the severity of mpox illness

Diagnostic technologies in Asia Pacific are key to progress toward health-related SDGs

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Single-dose smallpox vaccine could be effective against mpox

Study examines Mpox prevention with modified vaccinia Ankara (MVA)

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

The mpox viral load kinetics over time in various parts of the body

How do predicted ecological niches of the mpox virus compare with that of 99 mammal species?

New approach to detect misinformation in an emergent health domain on social media

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Knowledge and attitudes to mpox among GBMSM in Australia

Reports of Mpox disease following recent vaccination

Enveloped viruses show greater cross-species transmission, according to new research

Improved early detection and analysis of airborne pathogens with new liquid-coated air filters

Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

How medical manufacturing trends are evolving: From performance testing to 3D vision

Utilizing firefly liquid handling for laboratory developed tests

Immunopeptidomics offer new hope in cancer research

Mpox News and Research

Latest Mpox News and Research

How medical manufacturing trends are evolving: From performance testing to 3D vision

Utilizing firefly liquid handling for laboratory developed tests

Immunopeptidomics offer new hope in cancer research

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