Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.
Vibrational spectroscopy, a technique essential for analyzing chemical components in biological compounds, cells, organisms, tissues, and bioactivity products, plays a significant role in various fields. Its applications span many fields, from chemistry, microbiology, medicine, agriculture, and food science to forensics, botany, and environmental assessment, providing critical bioanalytical insights.
This article from Thermo Scientific outlines how Amira software was used as a tool to perform computed tomography to improve lung cancer surgery.
This article from Thermo Fisher Scientific outlines how analyzing complex structures can be done using
semi-automated bone segmentation.
This article talks about the immune system and the power of biomarkers.
This article from Thermo Fisher discusses a study published in 2022 where researchers used the Thermo Scientific™ Amira™ Software along with serial block-face scanning electron microscopy (SBF SEM). The result was that they were able to produce detailed 3D reconstructions of organelles.
This article from Thermo Fisher Scientific explores how Amira software can be used as a novel approach
for visualizing the developing skeleton in 3D.
This article outlines how Thermo Scientific Amira software was used to study actin waves through cryo-electron tomography.
In drug research and development, the effect that the hydration state of active pharmaceutical ingredients (APIs) has on crystallinity is an important consideration. Variations in crystallinity influence the stability, solubility, bio-availability, and dissolution rate of the drug. Therefore, knowing the effect that humidity has on the stability of different states is important, from both a regulatory and safety standpoint.
A new method to determine the onset relative humidity for a glass transition in an amorphous material was developed using the DVS. Water vapour can act as a plasticising agent in amorphous materials, causing a recrystallisation event below the glass transition temperature. This method calculates the threshold relative humidity for this moisture induced glass transition at a particular temperature.
The effects of humidity are evident in the stability and shelf-life of a variety of materials, formulations, and processing behaviour, especially food materials. This article discusses the advantages of a direct comparison method of three similar dried milk samples under varying humidity conditions, using optical microscopy in conjunction with the GenRH-A accessory and Mcell from Surface Measurement Systems.
Active materials with batch-to-batch variations present a major issue to the pharmaceutical industry. On the whole, any batch-to-batch variation is undesirable. The range of techniques available for the characterization, analysis, and discrimination of products that are chemically identical can be restricted by the nature of the materials, and the sensitivity to slight physicochemical variations between them.
Most pharmaceutical materials can exist in a desired crystalline state with an ordered lattice structure. There are several different crystalline forms of the same material available, such as polymorphs and/or solvated crystal forms.
Static SIMS can be used to confirm the presence of a drug, between other applications, by identifying molecular signals such as binding or dehydrating.
In this article, Hiden Analytical gives a detailed overview of plasma medicine - from the available
technology to the areas of application.
Learn about how to get more information from your samples using multiomics workflows in the updated Multiomics Methods Guide, now featuring Illumina’s most innovative platforms, NovaSeq™ X and X Plus Sequencing Systems.
Next-generation sequencing (NGS) will have a dramatic impact on healthcare in the next decade. But what are the real benefits of this trend? Learn more in this expert panel on accelerating precision medicine with low-cost whole-genome sequencing.
Metatranscriptomics takes on the daunting task of unraveling the delicate balance between humans and the trillions of microbial cells in residence. To comprehensively profile the microbiome, researchers are deploying multiomics to understand the microbiome’s role in human health.
Download this Gene Expression and Regulation eBook to explore how next-generation sequencing (NGS) is accelerating high impact studies using bulk or single-cell RNA-Seq applications.
Learn valuable insights for experimental success for single-cell sequencing. Discover how using single cell analysis can reveal cell types, functions and interactions within a complex biological microenvironment.
In this guide, learn how proteomics via next-generation sequencing (NGS) can be used to study biological processes, tumor biology, biomarker discovery and host-pathogen interactions, expanding a new era in proteogenomics.